Safety Data Sheet Propylene glycol Version 1.2 Revision Date: 10/30/2014 MSDS Number: 100000008803 1 / 16 Propylene glycol SECTION 1. PRODUCT AND COMPANY IDENTIFICATION
Symptoms of Chemical poisoning - Propylene Glycol including 10 medical symptoms and signs of Chemical poisoning - Propylene Glycol, alternative diagnoses, misdiagnosis, and correct diagnosis for Chemical poisoning - Propylene Glycol signs or Chemical poisoning - Propylene Glycol symptoms.
or cardiovascular, musculoskeletal, dermal, ocular, or metabolic effects in animals after inhalation exposure to propylene glycol. The highest NOAEL values and all reliable LOAEL values for systemic effects in each species and duration category for propylene glycol after inhalation exposure are reported in Table 2-1 and plotted in Fig ure 2-1.
Likely routes of exposure : Inhalation;Skin and eye contact SECTION 12: Ecological information 12.1. Toxicity No additional information available 12.2. Persistence and degradability No additional information available 12.3. Bioaccumulative potential Propylene Glycol Log Pow -0.92 12.4. Mobility in soil No additional information available 12.5.
hydraulic fluids, plasticizers and other products. Propylene glycol has low toxicity, is not acutely toxic, and does not irritate the skin. However, contact dermatitis has been reported from a wide variety of topical preparations. Inhalation of the vapors of propylene glycol may present
Also see: Propylene Glycol vs Vegetable Glycerine: Five Key Differences. Animal Studies on PG Inhalation. A lot of the older evidence on PG comes in the form of studies conducted on animals. It's hard to draw firm conclusions based on animal studies (unless you're mainly concerned about whether you should let your pet rat vape).
approved oral or inhalation toxicity values for it. However, DES has determined that 30,000 ppb is an appropriate interim drinking water guideline for propylene glycol based on current toxicity information and that there is also dietary exposure because of its use as a food additive.
(5), which contains information on inhalation chronic toxicity of propylene oxide and the RfC and the carcinogenic effects of propylene oxide including the unit cancer risk for inhalation exposure, and EPA's Summary Review of the Health Effects Associated with Propylene Oxide. (2) Uses
Rapidly absorbed from the GI tract and by inhalation. Propylene glycol: Metabolism . When testing for what toxin might you get a false positive in a patient with propylene glycol toxicity? Ethylene glycol. Propylene glycol: Treatment-No specific antidote - alcohol dehydrogenase inhibitors are not required since no toxic metabolites .
Although less toxic than EG, ingestion of propylene glycol (PG) may be associated with a toxic syndrome similar to the acute phase of EG toxicosis. The oral LD 50 of PG in dogs is ~9 mL/kg. In cats, ingestion of a diet containing 6%–12% PG can result in Heinz …
Propylene glycol is also present in propylene glycol alginate, which is known as E405. Propylene glycol is a compound which is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) under 21 CFR x184.1666 and is also approved by …
Jul 27, 2017· Propylene glycol is less toxic than ethylene glycol, which is the primary ingredient found in most standard antifreeze products. While it can still be harmful, propylene glycol is not as toxic as ethylene glycol, so accidental inhalation or ingestion would be not as disastrous to humans or animals.
–Product Safety Assessment- Propylene Glycol –Ethylene Glycol Toxicity –Ethylene Glycol- Wikipedia –Are Electronic Cigarettes Safe? –A Germ-Killing Vapor –Deposition and Fate of Inhaled Ethylene Glycol Vapor and Condensation Aerosol in the Rat –Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats.
Propylene Glycol USP grade is safe for human consumption, including inhalation. It is used as a germ killer in both solid and gas forms. It's in your prescription drugs.
SAFETY DATA SHEET Page 6 of 8 Current Issue Date: May 2018 150 OIL CHRONIC, PROLONGED OR REPEATED OVEREXPOSURE EFFECTS OF REPEATED OVEREXPOSURE: In rare cases, repeated excessive exposure to propylene glycol may cause central nervous system effects.
With a view to determining the safety of employing the vapors of propylene glycol and triethylene glycol in atmospheres inhabited by human beings, monkeys and rats were exposed continuously to high concentrations of these vapors for periods of 12 to 18 months. Equal numbers of control animals were maintained under physically similar conditions.
Treatment. If the toxicity is caused by ingesting of food that have high levels of propylene glycol, the local poison control must be contacted immediately and they should be brought to the hospital immediately.
exposed to low levels of ethylene glycol by inhalation for about a month were throat and upper respiratory tract irritation. Rats and mice chronically (long-term) exposed to ethylene glycol in their diet exhibited signs of kidney toxicity and liver effects. Several studies of rodents exposed orally or by inhalation showed
TIME COURSE: After ingestion, ethylene glycol is rapidly absorbed (within 1 to 4 hours) through the stomach.Following absorption, 80% or more of ethylene glycol is chemically converted by the body into toxic compounds. The course of ethylene glycol toxicity is classically divided into three broad overlapping categories of adverse health effects.
A series of inhalation studies with propylene glycol monomethyl ether (PGME) vapor were undertaken to characterize its subchronic toxicity in mice and chronic toxicity/oncogenicity in rats and mice. Groups of male and Fischer 344 rats and B6C3F1 mice were exposed to 0,300, 1,000, or 3,000 ppm vapor from 1 week to 2 years.
Nov 04, 2009· Decades before the e cigarette was invented, a study was conducted by Dr. Robertson of the University of Chicago's Billings Hospital in 1942 on inhalation of vaporized propylene glycol in .
Apr 24, 2017· Danger of Drinking Propylene Glycol . It is unlikely that propylene glycol toxicity will occur under normal circumstances. The most likely cause of such toxicity is an overdose of injectable medications that contain propylene glycol. Health professionals will be able to offer guidance as to the next steps that should be taken if this happens.
No pertinent data were located regarding health effects of propylene glycol in humans following oral or inhalation exposure. Propylene glycol is designated as a Generally Recognized As Safe (GRAS) food additive by the Food and Drug Administration (FDA), where it is approved for use as a direct food ingredient (FDA, 1982).
Apr 08, 2018· This means that, in normal dosage or exposure levels, propylene glycol breaks down in the body within 48 hours in individuals with healthy kidney and liver function and does not accumulate over time to create toxicity in the body. Propylene glycol is found in industrial-grade levels in products like antifreeze, polyurethane cushions, paints and .
The Dangers of Propylene Glycol
Short-term and subchronic vapor inhalation studies have shown that there are pronounced differences in the toxicological properties of ethylene glycol monomethyl ether (EGME) and propylene glycol monomethyl ether (PGME). Overexposure to EGME has resulted in …
While the toxicity of the main constituents of electronic cigarette (ECIG) liquids, nicotine, propylene glycol (PG), and vegetable glycerin (VG), has been assessed individually in separate studies, limited data on the inhalation toxicity of them is available when in mixtures.
Jun 27, 2015· Background. A shisha-pen is an electronic cigarette variant that is advertised to mimic the taste of a water pipe, or shisha. The aim of this study was to assess the potential harmful health effects caused by inhaling the vapor of a nicotine-free shisha-pen.