Dec 05, 2017· Ethylene Glycol Toxicity Treatment & Management. Approach Considerations Guidelines on the medical management of ethylene glycol poisoning are available from the Agency for Toxic Substances and Disease Registry. These include recommendations on prehospital, emergency department, and critical care treatment.
(2) Rats chronically exposed to ethylene glycol in their diet exhibited signs of kidney toxicity and liver effects. (5,7) Ocular irritation and lesions and pulmonary inflammation have been observed in rats, rabbits, and guinea pigs subchronically exposed by inhalation.
Toxicity. That is roughly 16 mL of 50% ethylene glycol for an 80 kg adult and 4 mL for a 20 kg child. Poison control centers often use more than a lick or taste in a child or more than a mouthful in an adult as a dose requiring hospital assessment.
Ethylene glycol poisoning: MedlinePlus Medical Encyclopedia
Apr 02, 2019· The toxic effects, other than the early state of alcohol intoxication, are mediated by ethylene glycol's metabolites. Initially there is a high osmolar gap due to the presence of ethylene glycol in the circulation.
Jun 06, 2013· Ethylene glycol (EG) is a common constituent of anti-freeze, coolants and other solvents and is responsible for both inadvertent and intentional poisoning. 1 Ethylene glycol poisoning may pose diagnostic difficulties if the history of ingestion is not volunteered, or if the presentation is delayed. The toxicity is because of biochemical features of high anion gap metabolic acidosis and an osmolar gap.
Ethylene glycol poisoning - Symptoms The first symptom of ethylene glycol ingestion is similar to the feeling caused by drinking alcohol. Ethylene glycol toxicity should be suspected in anyone who is severely ill after drinking an unknown. An overdose of ethylene glycol can damage the brain, .